Some garden friends said it was due to the “genetic cross” between Pen-Fu luffa (澎湖絲瓜) and bitter melon (苦瓜). It seemed plausible from the genetic point of view. We can insert the human insulin gene to the E-coli, which will dutifully make human insulin, which is the first biological.
It was a fascinating story of the race of making human insulin by Genentech and Biogen in 1970s (Genentech won the race). The discovery of restriction enzyme (so that DNA chain can be ‘cut’ open) by Stanley Cohen and Herbert Boyer paved the way for Paul Berg to develop recombinant DNA technology. Genentech was founded on the knowledge of the discovery of restriction enzyme and recombinant DNA technology. Herbert Boyer and Robert Swanson (the venture capitalist) were the cofounders of Genentech.
If the human and E-coli genes can work together, so can that of Pen-Fu luffa (澎湖絲瓜) and bitter melon (苦瓜). Besides our Pen-Fu luffa (澎湖絲瓜) and bitter melon (苦瓜) are in the same neighborhood, next to each other. The bees may carry the gene that makes cucurbitacins (葫蘆苦素, which is responsible for bitter taste) from bitter melon (苦瓜) to Pen-Fu luffa (澎湖絲瓜).
But, Ching-San Huang said that was not the case; the expert has spoken, so it shall be, we thus gave up the idea of no more bitter melon (苦瓜) in our garden.
Bitter melon (苦瓜) plants are delicate and slow-growing. Being in the same section with Chinese cucumber, they began to flourish only after the Chinese cucumber season was over.





















